Antitumor photosensitizer-6

Compound Ru2 (Antitumor photosensitizer-6) exhibits synergistic type I/II photosensitization and photocatalytic activities under illumination at 595 nm. It causes oxidative redox imbalance within cells, affecting biosynthesis and metabolic processes, leading to cell apoptosis (Apoptosis) . Compound Ru2 is applicable in studies of photodynamic therapy (PDT) .

FC1=C(C2=CC=C(C3=CC(C4=[N]([Ru+2]56([N]7=C8C=CC=C7)9[N]%10=C(C%11=CC=CC(C%12=[N]6C=CC=C%12)=[N]%115)C=CC=C%10)C=CC=C4)=[N]9C8=C3)S2)C%13=NSN=C%13C(C%14=CC=C(C%15=CC%16=[N]%17C(C%18=CC=CC=[N]%18[Ru+2]%19%20([N]%21=C%16C=CC=C%21)%17[N]%22=C(C%23=CC=CC(C%24=[N]%20C=CC=C%24)=[N]%23%19)C=CC=C%22)=C%15)S%14)=C1F.F[P-](F)(F)(F)(F)F.F[P-](F)(F)(F)(F)F.F[P-](F)(F)(F)(F)F.F[P-](F)(F)(F)(F)F