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IKZF3 degrader 1

Product Specifications

Target

Others|||IKZF|||Molecular Glues

Related Pathways

Immunology/Inflammation|||Others|||PROTAC

Bioactivity

IKZF3 Degrader 1 (compound 19a) acts as an effective IKZF3 degrader with an EC50 of 0.012 ?M and a minimal yield of 9.2%. It enhances the association of IKZF3 with Cereblon (CRBN), subsequently facilitating the ubiquitination and degradation of IKZF3.

Molecular Formula

C25H18BrCl3N2O5

Molecular Weight

612.68

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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