IKZF3 degrader 1
Product Specifications
Target
Others|||IKZF|||Molecular Glues
Related Pathways
Immunology/Inflammation|||Others|||PROTAC
Bioactivity
IKZF3 Degrader 1 (compound 19a) acts as an effective IKZF3 degrader with an EC50 of 0.012 ?M and a minimal yield of 9.2%. It enhances the association of IKZF3 with Cereblon (CRBN), subsequently facilitating the ubiquitination and degradation of IKZF3.
Molecular Formula
C25H18BrCl3N2O5
Molecular Weight
612.68
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/240554098091360257/T89846
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