MMAF intermediate 2
Product Specifications
CAS Number
864238-20-0
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
MMAFintermediate 2 serves as a precursor in the synthesis of MMAF (Monomethylauristatin F) . MMAF is a potent inhibitor of tubulin polymerization and a cytotoxic component of classical antibody-drug conjugates (ADCs), including Vorsetuzumab mafodotin and SGN-CD19A, serving as the ADC Cytotoxin.
Smiles
[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(OC)=O)=O)C)(OC)[C@@]2(CCCN2)[H].Cl
Molecular Formula
C19H29ClN2O4
Molecular Weight
384.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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