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MMAF intermediate 2

Product Specifications

CAS Number

864238-20-0

Target

ADC Cytotoxin

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

MMAFintermediate 2 serves as a precursor in the synthesis of MMAF (Monomethylauristatin F) . MMAF is a potent inhibitor of tubulin polymerization and a cytotoxic component of classical antibody-drug conjugates (ADCs), including Vorsetuzumab mafodotin and SGN-CD19A, serving as the ADC Cytotoxin.

Smiles

[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(OC)=O)=O)C)(OC)[C@@]2(CCCN2)[H].Cl

Molecular Formula

C19H29ClN2O4

Molecular Weight

384.9

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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