Exatecan Intermediate 5
Product Specifications
CAS Number
143655-70-3
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
Exatecan Intermediate 5 serves as an intermediate in the synthesis of Exatecan (DX-8951), a DNA topoisomerase I (topoisomerase I) inhibitor with an IC50 of 2.2 ?M (0.975 ?g/mL), utilized in cancer research. This intermediate is also employed in the production of Antibody-Drug Conjugates (ADCs) .
Smiles
O=C(NC1=CC(F)=C(C2=C1C(=O)C(NC(=O)C)CC2)C)C
Molecular Formula
C15H17FN2O3
Molecular Weight
292.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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