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Exatecan Intermediate 5

Product Specifications

CAS Number

143655-70-3

Target

ADC Cytotoxin

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

Exatecan Intermediate 5 serves as an intermediate in the synthesis of Exatecan (DX-8951), a DNA topoisomerase I (topoisomerase I) inhibitor with an IC50 of 2.2 ?M (0.975 ?g/mL), utilized in cancer research. This intermediate is also employed in the production of Antibody-Drug Conjugates (ADCs) .

Smiles

O=C(NC1=CC(F)=C(C2=C1C(=O)C(NC(=O)C)CC2)C)C

Molecular Formula

C15H17FN2O3

Molecular Weight

292.31

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/235808271020064820/T89654

Available Sizes

Curated Selection

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