Exatecan Intermediate 5
Product Specifications
CAS Number
143655-70-3
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
Exatecan Intermediate 5 serves as an intermediate in the synthesis of Exatecan (DX-8951), a DNA topoisomerase I (topoisomerase I) inhibitor with an IC50 of 2.2 ?M (0.975 ?g/mL), utilized in cancer research. This intermediate is also employed in the production of Antibody-Drug Conjugates (ADCs) .
Smiles
O=C(NC1=CC(F)=C(C2=C1C(=O)C(NC(=O)C)CC2)C)C
Molecular Formula
C15H17FN2O3
Molecular Weight
292.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
M3885-80B-PE 100 µL
MHC Class 1, H-2Kb (MHC Class I H-2Kb, H-2 Class I Histocompatibility Antigen K-B alpha Chain, H-2K (B), H2-K1, H-2K, H2-K, H-2K (d), MGC7052, MGC184092) (PE) discontinued, see M3885-72D-PE
Ask
View Details 
