FOSL1 degrader 1
Product Specifications
Target
PROTACs|||DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair|||PROTAC|||Cell Cycle/Checkpoint
Bioactivity
FOSL1 degrader 1 (4) is a potent T-5224-PROTAC that effectively degrades FOSL1 (AP-1), thereby suppressing the expression of cancer stemness genes in HNSCC. By degrading FOSL1, it inhibits tumor growth and effectively eliminates cancer stem cells in HNSCC tumors. This compound demonstrates an efficacy 30 to 100 times greater than that of T-5224.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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