PROTAC PARP1 degrader-2
Product Specifications
CAS Number
2923686-62-6
Bioactivity
PROTACPARP1 degrader-2 (Compound 72) is a potent PROTAC degrader of PARP, achieving a DC50 of less than 10 nM in MDA-MB-231 cells. Additionally, this compound effectively inhibits the viability of MDA-MB-436 cells with an IC50 of less than 100 nM.
Smiles
O=C(NC1CCN(C2=CC=C3C(=O)N(C(=O)C3=C2)C4C(=O)NC(=O)CC4)CC1)C5=NC(F)=C(C=C5)N6CCN(CC=7C=CC=8N=C(C(=O)NC8C7F)C)CC6
Molecular Formula
C38H37F2N9O6
Molecular Weight
753.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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