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JAK2/FLT3-IN-3

Product Specifications

CAS Number

3038183-53-5

Bioactivity

JAK2/FLT3-IN-3 (11r) is a dual inhibitor of FLT3 and JAK2, with IC50 values respectively at 0.51 nM for FLT3, 2.01 nM for JAK2, and 104.40 nM for JAK3. It can induce apoptosis and exhibits anticancer activity.

Smiles

O=C(NC1=CC=C(C=C1)C(=O)C)N2CCN(C3=NC(=NC=C3C)NC4=CC=C(C=C4)N5CCC(N6CCN(C)CC6)CC5)CC2

Molecular Formula

C34H45N9O2

Molecular Weight

611.78

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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