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OPB-171775

Product Specifications

CAS Number

2131210-15-4

Bioactivity

OPB-171775 is a molecular glue that forms a ternary complex with phosphodiesterase 3A (PDE3A) and schlafen family member 12 (SLFN12) . This compound induces cell death mediated by SLFN12 RNase, activates the SLFN12 RNase-associated GCN2 signaling pathway, and demonstrates antitumor activity.

Smiles

FC1=C(C=CC(OCC(C)(C)O)=C1F)C=2[C@H](C)CC(=O)NN2

Molecular Formula

C15H18F2N2O3

Molecular Weight

312.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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