OPB-171775
Product Specifications
CAS Number
2131210-15-4
Bioactivity
OPB-171775 is a molecular glue that forms a ternary complex with phosphodiesterase 3A (PDE3A) and schlafen family member 12 (SLFN12) . This compound induces cell death mediated by SLFN12 RNase, activates the SLFN12 RNase-associated GCN2 signaling pathway, and demonstrates antitumor activity.
Smiles
FC1=C(C=CC(OCC(C)(C)O)=C1F)C=2[C@H](C)CC(=O)NN2
Molecular Formula
C15H18F2N2O3
Molecular Weight
312.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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MBS6314373-02 5x 0.2 mL
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