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KRAS G12C inhibitor 68

Product Specifications

CAS Number

3034851-27-6

Target

Ras, Kras

Related Pathways

MAPK

Bioactivity

KRAS G12C inhibitor 68 (compound I-063) serves as a potent inhibitor of KRAS G12C, exhibiting an IC50 of 7 nM and demonstrating antitumor activity.

Smiles

C(F)(F)C1=C2C(N3[C@]([C@@H](C3)N4CCN(C(C=C)=O)CC4)(CC=C2)[H])=CC(=N1)N5[C@H](C)C[C@H](CC5)C6=C(N=CC=C6C)C7(OC)COC7

Molecular Formula

C35H44F2N6O3

Molecular Weight

634.76

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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