PROTAC erf3a Degrader-1

PROTACerf3a Degrader-1 (Compound C63) is an orally active PROTACerf3a degrader capable of inhibiting the proliferation of cancer cells (such as 22Rv1) . It is utilized in the research of various cancers including prostate, ovarian, liver, cervical, leukemia, and breast cancer.

C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@@](CC3)(NC(=O)C=C4)[H])(CC1)[H])[H])(CC[C@@H]2C(NC5=CC(N[C@H]6C[C@H](NC7=C8C(C(=O)N(C8=O)[C@@H]9C(=O)NC(=O)CC9)=CC=C7)CCC6)=CC=C5)=O)[H]