SB 242084 monohydrochloride
Product Specifications
CAS Number
1260505-34-7
Bioactivity
SB 242084 monohydrochloride is a selective, competitive, and high-affinity 5-HT2C receptor antagonist (pKi=9.0) that can cross the blood-brain barrier. This compound enhances the basal activity of dopaminergic neurons in the ventral tegmental area (VTA) and increases dopamine release in the nucleus accumbens. Additionally, SB 242084 monohydrochloride boosts the expression of mitochondrial genes and oxidative metabolism via the 5-HT2A receptor. Its potential for research in anxiety, depression, negative symptoms of schizophrenia, and acute organ damage is significant.
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Cl.O=C(NC1=CN=C(OC2=CC=CN=C2C)C=C1)N3C4=CC(Cl)=C(C=C4CC3)C
Molecular Formula
C21H20Cl2N4O2
Molecular Weight
431.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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