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BRPF1B/TRIM24-IN-1

Product Specifications

CAS Number

1242907-48-7

Bioactivity

BRPF1B/TRIM24-IN-1 (compound 34) is a potent inhibitor of TRIM24, BRPF1, and BRPF2, with IC50 values of 0.43 ?M, 0.34 ?M, and 1.75 ?M respectively. The dissociation constants (KD) for its binding with the bromodomains of TRIM24, BRPF1, and BRD1 are 222 nM, 137 nM, and 1130 nM respectively.

Smiles

O=C1N(C2=CC(OC3=CC=C(OC)C=C3)=C(C=C2N1C)NS(=O)(=O)C4=CC=C(OC)C(OC)=C4)C

Molecular Formula

C24H25N3O7S

Molecular Weight

499.54

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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