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Adenosine receptor antagonist 5

Product Specifications

Target

Adenosine Receptor

Related Pathways

GPCR/G Protein, Neuroscience

Bioactivity

Adenosine receptor antagonist5 (Compound 39) serves as a selective antagonist for the human adenosine A3 receptor (hA3R) with a Ki of 12 nM. This compound inhibits the accumulation of IB-MECA-induced cAMP in NCI-H1792 cells and suppresses the proliferation of LK-2 and NCI-H1792 cancer cells. Additionally, Adenosine receptor antagonist5 exhibits a rapid metabolism rate in human liver microsomes.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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