Ap4A tetraammonium

Ap4A tetraammonium, a conserved second messenger across organisms from bacteria to humans, binds and activates the transcription of MITF downstream genes in conjunction with histidine triad nucleotide-binding protein 1 (HINT1) . Additionally, Ap4A tetraammonium induces cell apoptosis (apoptosis) .

O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP(OP(OC[C@H]2O[C@@H](N3C4=NC=NC(N)=C4N=C3)[C@@H]([C@@H]2O)O)([O-])=O)([O-])=O)([O-])=O)([O-])=O)N5C6=NC=NC(N)=C6N=C5.[NH4+].[NH4+].[NH4+].[NH4+]