Rp-8-pCPT-cGMPS
Product Specifications
CAS Number
153660-04-9
Bioactivity
Rp-8-pCPT-cGMPS is a competitive inhibitor of cyclic guanosine monophosphate (cGMP) -dependent protein kinase (PKG) with a Ki of 0.5 μM. This compound exhibits increased lipophilicity, allowing it to penetrate cell membranes more readily and achieve sufficient intracellular concentrations to inhibit PKG. Rp-8-pCPT-cGMPS is useful for researching the activity and function of PKG in platelets.
Smiles
S(C=1N(C2=C(N1)C(=O)N=C(N)N2)[C@H]3[C@H](O)[C@]4([C@](O3)(COP(=O)(S)O4)[H])[H])C5=CC=C(Cl)C=C5
Molecular Formula
C16H15ClN5O6PS2
Molecular Weight
503.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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