NT376
Product Specifications
CAS Number
2820208-97-5
Bioactivity
NT376 is a potent and selective inhibitor of class IIa Histone deacetylases (HDAC), exhibiting an IC50 value of 32 nM and demonstrating efficacy similar to NT160 (IC50 = 46 nM) in HT-29 cells. This compound is a promising candidate for research into various cancers and central nervous system (CNS) disorders, including Alzheimers and Huntingtons diseases.
Smiles
C(F)(F)(F)C1=NC(=NO1)C2=CC(F)=C(C(N[C@@H](CN(CC3=CC=CC=C3)C)C)=O)C=C2
Molecular Formula
C21H20F4N4O2
Molecular Weight
436.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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