NT376
Product Specifications
CAS Number
2820208-97-5
Bioactivity
NT376 is a potent and selective inhibitor of class IIa Histone deacetylases (HDAC), exhibiting an IC50 value of 32 nM and demonstrating efficacy similar to NT160 (IC50 = 46 nM) in HT-29 cells. This compound is a promising candidate for research into various cancers and central nervous system (CNS) disorders, including Alzheimers and Huntingtons diseases.
Smiles
C(F)(F)(F)C1=NC(=NO1)C2=CC(F)=C(C(N[C@@H](CN(CC3=CC=CC=C3)C)C)=O)C=C2
Molecular Formula
C21H20F4N4O2
Molecular Weight
436.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6183081-01 0.1 mL
EXOSC5 (exosome Component 5, MGC111224, MGC12901, RRP41B, RRP46, Rrp46p, hRrp46p, p12B) (HRP)
Ask
View Details MBS6183081-02 5x 0.1 mL
EXOSC5 (exosome Component 5, MGC111224, MGC12901, RRP41B, RRP46, Rrp46p, hRrp46p, p12B) (HRP)
Ask
View Details