ESAT6 Epitope

ESAT6 Epitope is a known CD4+ T cell epitope within the Early Secretory Antigenic Target 6 (ESAT6), demonstrating nanoscale affinity (IC50=180 nM) for Major Histocompatibility Complex MHC class I. Additionally, ESAT6 Epitope can enhance the anti-tuberculosis cellular immunity initiated by the Bacille Calmette-Guérin vaccine.

C([C@@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(O)=O)=O)CCC(N)=O)=O)[C@H](CC)C)=O)C)=O)CO)=O)C)=O)C)=O)C)=O)CCC(O)=O)=O)[C@H](CC)C)=O)=O)C)=O)=O)CC(N)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCSC)N)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)C=2C=3C(NC2)=CC=CC3