What is the catalog number for LSD1-IN-34?

The catalog number for LSD1-IN-34 is T89432.

What sizes are available for LSD1-IN-34?

LSD1-IN-34 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does LSD1-IN-34 come in?

LSD1-IN-34 is available in 2 different pack sizes.

Is LSD1-IN-34 in stock?

LSD1-IN-34 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures LSD1-IN-34?

LSD1-IN-34 is manufactured by Molfinity.

What is the estimated delivery time for LSD1-IN-34?

Estimated delivery time for LSD1-IN-34 is approximately 10 business day(s), depending on your location.

LSD1-IN-34

Product Specifications

Target

Monoamine Oxidase, Histone Demethylase, TGF-beta/Smad

Related Pathways

Stem Cells, Neuroscience, Chromatin/Epigenetic

Bioactivity

LSD1-IN-34 (Compound 7d) is an orally effective inhibitor of lysine-specific demethylase (LSD) and monoamine oxidase (MAO), exhibiting IC50 values of 4.51 nM for LSD1 and 18.46 nM for MAO A. This compound inhibits activation of neonatal rat cardiac fibroblasts (NRCF) induced by angiotensin II (Ang II) and shows no significant toxicity at 20 μM. LSD1-IN-34 also inhibits the TGFβ/Smad signaling pathway, contributing to the improvement of heart failure in mice. Moreover, it demonstrates favorable pharmacokinetic properties in rats.