PDE4-IN-18
Product Specifications
Target
Interleukin, PDE, TNF
Related Pathways
Metabolism, Immunology/Inflammation, Apoptosis
Bioactivity
PDE4-IN-18 (compound 1l) is a PDE4 inhibitor with an IC50 value of 1.55 μM and exhibits anti-inflammatory activity. It mitigates inflammation by reducing excessive infiltration of immune cells and enthesial formation, as well as decreasing the mRNA expression of pro-inflammatory cytokines (such as TNF-α and IL-6) in the synovial tissues. PDE4-IN-18 is suitable for research into rheumatoid arthritis and psoriasis.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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