PDE4-IN-18
Product Specifications
Target
Interleukin|||PDE|||TNF
Related Pathways
Metabolism|||Immunology/Inflammation|||Apoptosis
Bioactivity
PDE4-IN-18 (compound 1l) is a PDE4 inhibitor with an IC50 value of 1.55 ?M and exhibits anti-inflammatory activity. It mitigates inflammation by reducing excessive infiltration of immune cells and enthesial formation, as well as decreasing the mRNA expression of pro-inflammatory cytokines (such as TNF-? and IL-6) in the synovial tissues. PDE4-IN-18 is suitable for research into rheumatoid arthritis and psoriasis.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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