What is the catalog number for PDE4-IN-18?

The catalog number for PDE4-IN-18 is T89424.

What sizes are available for PDE4-IN-18?

PDE4-IN-18 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does PDE4-IN-18 come in?

PDE4-IN-18 is available in 2 different pack sizes.

Is PDE4-IN-18 in stock?

PDE4-IN-18 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PDE4-IN-18?

PDE4-IN-18 is manufactured by Molfinity.

What is the estimated delivery time for PDE4-IN-18?

Estimated delivery time for PDE4-IN-18 is approximately 10 business day(s), depending on your location.

PDE4-IN-18

Product Specifications

Target

Interleukin, PDE, TNF

Related Pathways

Metabolism, Immunology/Inflammation, Apoptosis

Bioactivity

PDE4-IN-18 (compound 1l) is a PDE4 inhibitor with an IC50 value of 1.55 μM and exhibits anti-inflammatory activity. It mitigates inflammation by reducing excessive infiltration of immune cells and enthesial formation, as well as decreasing the mRNA expression of pro-inflammatory cytokines (such as TNF-α and IL-6) in the synovial tissues. PDE4-IN-18 is suitable for research into rheumatoid arthritis and psoriasis.