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WX8

Product Specifications

CAS Number

232935-92-1

Bioactivity

WX8 (Ro 91-4714) is an ATP-competitive inhibitor of PIKFYVE, displaying Kd values of 0.9 nM for PIKFYVE and 340 nM for PIP4K2C. This compound inhibits lysosomal fission without affecting homotypic lysosome fusion. WX8 (Ro 91-4714) is applicable in research on autophagy-dependent cancers.

Smiles

N(=CC1=CNC=2C=CC=CC12)NC=3N=C(N=C(N3)N4CCOCC4)NC=5C=CC=CC5

Molecular Formula

C22H22N8O

Molecular Weight

414.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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