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Grp94 Inhibitor-2

Product Specifications

Target

HSP

Related Pathways

Cytoskeletal Signaling, Metabolism

Bioactivity

Grp94 Inhibitor-2 (compound 23) is a cyclopropane analog that exhibits high affinity for Glucose Regulated Protein 94 (Grp94), with dissociation constants (Kd) of 0.48 μM for Grp94 and 0.65 μM for Hsp90α.

Smiles

FC(C=C1)=CC=C1CC2=CC=CC=C2CCC3=C(Cl)C(O)=CC(O)=C3C(N[C@@H]4C[C@@H](O)C4)=O

Molecular Formula

C26H25ClFNO4

Molecular Weight

469.94

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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