HSP70-IN-6
Product Specifications
Target
HSP|||Apoptosis|||Bcl-2 Family
Related Pathways
Apoptosis|||Cytoskeletal Signaling|||Metabolism
Bioactivity
HSP70-IN-6 (Compound JL-15) acts as an inhibitor of the Hsp70-Bim protein-protein interactions (PPI) with an IC50 value of 70 nM. It induces apoptosis in chronic myeloid leukemia (CML) cells with EC50 values of 0.43 ?M (BV173), 0.88 ?M (K562), and 0.19 ?M (K562-R3) .
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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