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HSP70-IN-6

Product Specifications

Target

HSP|||Apoptosis|||Bcl-2 Family

Related Pathways

Apoptosis|||Cytoskeletal Signaling|||Metabolism

Bioactivity

HSP70-IN-6 (Compound JL-15) acts as an inhibitor of the Hsp70-Bim protein-protein interactions (PPI) with an IC50 value of 70 nM. It induces apoptosis in chronic myeloid leukemia (CML) cells with EC50 values of 0.43 ?M (BV173), 0.88 ?M (K562), and 0.19 ?M (K562-R3) .

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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