What is the catalog number for PROTAC SMARCA2/4-degrader-17?

The catalog number for PROTAC SMARCA2/4-degrader-17 is T89356.

What sizes are available for PROTAC SMARCA2/4-degrader-17?

PROTAC SMARCA2/4-degrader-17 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does PROTAC SMARCA2/4-degrader-17 come in?

PROTAC SMARCA2/4-degrader-17 is available in 2 different pack sizes.

Is PROTAC SMARCA2/4-degrader-17 in stock?

PROTAC SMARCA2/4-degrader-17 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PROTAC SMARCA2/4-degrader-17?

PROTAC SMARCA2/4-degrader-17 is manufactured by Molfinity.

What is the estimated delivery time for PROTAC SMARCA2/4-degrader-17?

Estimated delivery time for PROTAC SMARCA2/4-degrader-17 is approximately 10 business day(s), depending on your location.

PROTAC SMARCA2/4-degrader-17

Product Specifications

CAS Number

2568276-88-8

Bioactivity

PROTAC SMARCA2/4-degrader-17 (Compound I-345) is a PROTAC degrader targeting the catalytic subunits SMARCA2 and SMARCA4 of the SWI/SNF complex. It degrades SMARCA2 in A549 cells with a DC50<100 nM and SMARCA4 in MV411 cells, also demonstrating a DC50<100 nM.

Smiles

NC1=C(N2CC3N(C(C2)CC3)C=4N=CC(=CN4)C5=C(C)C=C(CC(N[C@H](C(=O)N6[C@H](C(NCC7=CC=C(C=C7)C8=C(C)N=CS8)=O)C[C@@H](O)C6)C(C)(C)C)=O)C=C5)C=C(N=N1)C9=C(O)C=CC=C9