PF-DcpSi
Product Specifications
CAS Number
2092917-19-4
Bioactivity
PF-DcpSi is an mRNA decapping scavenger enzyme (DcpS) inhibitor with an IC50 of 0.11 nM. When administered intraperitoneally at a dose of 30 mg/kg, PF-DcpSi can improve the disease phenotype in a mouse model of spinal muscular atrophy (SMA) .
Smiles
N#CC1=CC(F)=CC(OCC=2C=CC=C3N=C(N=C(N)C32)N)=C1
Molecular Formula
C16H12FN5O
Molecular Weight
309.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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