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PF-DcpSi

Product Specifications

CAS Number

2092917-19-4

Bioactivity

PF-DcpSi is an mRNA decapping scavenger enzyme (DcpS) inhibitor with an IC50 of 0.11 nM. When administered intraperitoneally at a dose of 30 mg/kg, PF-DcpSi can improve the disease phenotype in a mouse model of spinal muscular atrophy (SMA) .

Smiles

N#CC1=CC(F)=CC(OCC=2C=CC=C3N=C(N=C(N)C32)N)=C1

Molecular Formula

C16H12FN5O

Molecular Weight

309.3

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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