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Anticonvulsant agent 5

Product Specifications

Target

Sodium Channel|||GABA Receptor

Related Pathways

Neuroscience|||Membrane transporter/Ion channel

Bioactivity

Compound 5c (Anticonvulsant agent 5) exhibits high affinity for GABAA receptors (GABAA receptor) and NaV1.3 receptors (NaV1.3 receptor) . In the murine psychomotor seizure test, it demonstrated anticonvulsant activity with an ED50 of 107 mg/kg. Additionally, Compound 5c shows neuroprotective effects against Kainic acid with an IC50 of 113 ?M and possesses blood-brain barrier (BBB) permeability.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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