PolQi1

Product Specifications

CAS Number

2607139-80-8

Target

DNA/RNA Synthesis

Related Pathways

DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

Purity

0.9897

Bioactivity

PolQi1 is a highly efficient and selective Pol? (DNA polymerase theta) inhibitor with an IC50 of 2 nM, showing potential for cancer therapy.

Smiles

C(N(C)C1=C(F)C(Cl)=C(F)C=C1)(=O)[C@H]2N(C(=O)NC2)C3=CC(C(F)(F)F)=CC(C)=N3

Molecular Formula

C18H14ClF5N4O2

Molecular Weight

448.77

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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