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Sutetinib

Product Specifications

CAS Number

1259519-20-4

Bioactivity

Sutetinib is an orally effective tyrosine kinase inhibitor that targets enzymes linked to tumor growth and angiogenesis, such as VEGFR (VEGFR-1/2/3 with Ki= 0.009 µM), PDGFR (PDGFR-?/? with Ki= 0.008 µM), and the proto-oncogene cKIT. It inhibits the proliferation, migration, and tubular structure formation of endothelial and fibroblast cells, demonstrating antitumor activity across various cancer cell lines.

Smiles

N(C=1C2=C(C=C(OCC)C(NC(/C=C/CN(C)C)=O)=C2)N=CC1C#N)C3=CC(C#C)=CC=C3

Molecular Formula

C26H25N5O2

Molecular Weight

439.51

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/235808112848666633/T89333

Available Sizes

Curated Selection

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