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PROTAC erf3a Degrader-2

Product Specifications

CAS Number

3033871-15-4

Bioactivity

PROTACerf3a Degrader-2 (Compound C59) is an orally active degrader of PROTACerf3a that suppresses the expression levels of SRD5A3 and GSPT1 (eRF3a) . It inhibits the proliferation of cancer cells, such as in 22Rv1. PROTACerf3a Degrader-2 is utilized in research for various cancers including prostate, ovarian, liver, cervical, leukemia, and breast cancer.

Smiles

C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@@](CC3)(NC(=O)C=C4)[H])(CC1)[H])[H])(CC[C@@H]2C(NC5=CC(N[C@H]6C[C@H](NC7=C8C(C(=O)N(C8=O)C9C(=O)NC(=O)CC9)=CC=C7)CCC6)=CC=C5)=O)[H]

Molecular Formula

C44H52N6O6

Molecular Weight

760.92

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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