PROTAC NCOA4 degrader-1
Product Specifications
Target
PROTACs, Ferroptosis
Related Pathways
PROTAC, Apoptosis
Bioactivity
PROTACNCOA4 degrader-1 (Compound V3) is a PROTAC-based degrader of NCOA4, exhibiting a DC50 of 3 nM in HeLa cells. Besides acting as a ferroptosis inhibitor, this compound effectively reduces the levels of NCOA4 and decreases intracellular ferrous (Fe2+) levels. Moreover, PROTACNCOA4 degrader-1 ameliorates liver damage in a CCl4-induced acute liver injury model.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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