What is the catalog number for NLRP3-IN-34?

The catalog number for NLRP3-IN-34 is T89270.

What sizes are available for NLRP3-IN-34?

NLRP3-IN-34 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does NLRP3-IN-34 come in?

NLRP3-IN-34 is available in 2 different pack sizes.

Is NLRP3-IN-34 in stock?

NLRP3-IN-34 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NLRP3-IN-34?

NLRP3-IN-34 is manufactured by Molfinity.

What is the estimated delivery time for NLRP3-IN-34?

Estimated delivery time for NLRP3-IN-34 is approximately 10 business day(s), depending on your location.

NLRP3-IN-34

Product Specifications

CAS Number

1392502-55-4

Bioactivity

NLRP3-IN-34 (Compound T10) acts as an inhibitor of the NLRP3 inflammasome. It blocks the production of reactive oxygen species (ROS) and impedes the formation of NLRP3 inflammasome-dependent IL-1β (J774A.1, IC50 of 0.48 μM), while also inhibiting pyroptosis (cell suicide) . Additionally, NLRP3-IN-34 displays anti-inflammatory activity in a C57BL/6 mouse model for DSS-induced peritonitis.