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Z-VAD

Product Specifications

CAS Number

162852-62-2

Target

Apoptosis, Caspase

Related Pathways

Proteases/Proteasome, Apoptosis

Purity

0.98961

Bioactivity

Z-VAD is an irreversible pan-caspase inhibitor capable of suppressing multiple caspases including caspase-3, -6, -7, -8, and -9. Z-VAD induces autophagy and necrosis in tumour cells, delays tumour growth, exhibits anti-angiogenic activity, and enhances the sensitivity of breast and lung cancer cells to radiotherapy.

Smiles

C(OC(N[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)C)=O)C(C)C)=O)C1=CC=CC=C1

Molecular Formula

C20H27N3O8

Molecular Weight

437.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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