PPARα agonist 4
Product Specifications
Target
Reactive Oxygen Species, PPAR, STING
Related Pathways
Immunology/Inflammation, Metabolism, NF-κB, DNA Damage/DNA Repair
Bioactivity
PPARα agonist4 (compound BH400) is a PPARα agonist with an EC50 of 1.2 μM. In addition to its primary activity, PPARα agonist4 inhibits STING with an IC50 of 8.1 μM. It also reduces reactive oxygen species production induced by CoCl2 and decreases IL-6 secretion prompted by LPS. Further, PPARα agonist4 restores the decreased expression of PCG1α caused by LPS.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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