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PPAR? agonist 4

Product Specifications

Target

Reactive Oxygen Species|||PPAR|||STING

Related Pathways

Immunology/Inflammation|||Metabolism|||NF-?B|||DNA Damage/DNA Repair

Bioactivity

PPAR? agonist4 (compound BH400) is a PPAR? agonist with an EC50 of 1.2 ?M. In addition to its primary activity, PPAR? agonist4 inhibits STING with an IC50 of 8.1 ?M. It also reduces reactive oxygen species production induced by CoCl2 and decreases IL-6 secretion prompted by LPS. Further, PPAR? agonist4 restores the decreased expression of PCG1? caused by LPS.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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