M4 mAChR Modulator-1
Product Specifications
Target
AChR
Related Pathways
Neuroscience
Bioactivity
M4 mAChR Modulator-1 (compound 23i) acts as a positive allosteric modulator (PAM) of the M4 mAChR. It demonstrates a stronger synergistic effect in β-arrestin recruitment compared to G protein activation when interacting with ACh. Additionally, while its PAM effects are weaker in G protein-mediated responses, they are more potent in β-arrestin recruitment.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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