Segigratinib hydrochloride
Product Specifications
CAS Number
2847066-15-1
Bioactivity
Segigratinib hydrochloride (3D185) is an effective inhibitor of FGFR1/2/3 and CSF-1R, exhibiting IC50 values of 0.5, 1.3, 3.6, and 3.8 nM for FGFR1, FGFR2, FGFR3, and CSF-1R, respectively. This compound possesses anti-tumor activity.
Smiles
Cl.O=C(NC1=NNC=2N=C(C=CC12)C=3C(Cl)=C(OC)C=C(OC)C3Cl)C4=CC=C(C=C4)N5CCNC(C)(C)C5
Molecular Formula
C27H29Cl3N6O3
Molecular Weight
591.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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