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LL-K12-18

Product Specifications

Target

Molecular Glues, CDK

Related Pathways

PROTAC, Cell Cycle/Checkpoint

Purity

0.9977

Bioactivity

LL-K12-18 is a dual-site molecular gel that enhances protein-protein interactions (PPIs) between CDK12-DDB1 complexes thereby promoting the degradation of Cyclin K. It potently inhibits tumor cell gene transcription and anti-proliferation.

Smiles

CCN1C2=NC(N3CCN(C(CN(CC)CC)=O)CC3)=NC(NCC4=NC5=CC(Cl)=C(Cl)C=C5N4)=C2N=C1

Molecular Formula

C25H32Cl2N10O

Molecular Weight

559.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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