LL-K12-18
Product Specifications
Target
Molecular Glues, CDK
Related Pathways
PROTAC, Cell Cycle/Checkpoint
Purity
0.9977
Bioactivity
LL-K12-18 is a dual-site molecular gel that enhances protein-protein interactions (PPIs) between CDK12-DDB1 complexes thereby promoting the degradation of Cyclin K. It potently inhibits tumor cell gene transcription and anti-proliferation.
Smiles
CCN1C2=NC(N3CCN(C(CN(CC)CC)=O)CC3)=NC(NCC4=NC5=CC(Cl)=C(Cl)C=C5N4)=C2N=C1
Molecular Formula
C25H32Cl2N10O
Molecular Weight
559.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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