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INOS/COX-2-IN-3

Product Specifications

Target

COX, NO Synthase

Related Pathways

Immunology/Inflammation, Neuroscience

Bioactivity

INOS/COX-2-IN-3 (compound 7d) is a dual inhibitor of iNOS and COX-2, demonstrating potential anti-inflammatory activity in LPS-induced RAW 264.7 cells (IC50=3.48 μM) . This compound exhibits good plasma stability, oral activity, and gastric safety. Its inhibitory effects on iNOS and COX-2 expressions are 5.43 times and 2.37 times higher than those of Indomethacin, respectively.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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