INOS/COX-2-IN-3
Product Specifications
Target
COX, NO Synthase
Related Pathways
Immunology/Inflammation, Neuroscience
Bioactivity
INOS/COX-2-IN-3 (compound 7d) is a dual inhibitor of iNOS and COX-2, demonstrating potential anti-inflammatory activity in LPS-induced RAW 264.7 cells (IC50=3.48 μM) . This compound exhibits good plasma stability, oral activity, and gastric safety. Its inhibitory effects on iNOS and COX-2 expressions are 5.43 times and 2.37 times higher than those of Indomethacin, respectively.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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