ULK1-IN-3

Metabolism, Cytoskeletal Signaling, Apoptosis, Chromatin/Epigenetic, DNA Damage/DNA Repair, Immunology/Inflammation, PI3K/Akt/mTOR signaling, NF-κB, Autophagy

ULK1-IN-3 (Compound 8) is a novel chalcone-based potential ULK1 inhibitor. This compound inhibits the cell cycle, autophagy, and induces apoptosis and oxidative stress in colorectal cancer cell lines.